– Did you check the efficacy of DVD-444 TrxR1 inhibition (TrxR1 expression, Trx status) in different cell lines?
– Responses with respect GPX1 and GPX4 expression and GSH content are quite similar among cell lines of different species, while GR and GSTtt are not. Why?
– In view of the above, human cells look resistant to apoptosis induction, but more sensitive to the cytostatic effect. Is that true?
Did you check the efficacy of DVD-444 in normal cell lines
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